
The Internet Book of Critical Care Podcast IBCC Episode 49 - Septic Shock
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Aug 8, 2019 This podcast covers patient identification, risk stratification, fluids, and vasopressors in septic shock. It discusses the flaws of the Rivers trial and the slow adaptation of the Surviving Sepsis Campaign. The importance of bedside assessment, antibiotic selection, source control, and a patient-centered approach is emphasized. The risks and benefits of steroid use in septic shock, metabolic resuscitation with vitamin C, and optimal heart rate for patients are also discussed.
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Rivers Trial Limitations
- The modern sepsis management era began with the Rivers trial in 2001, introducing early goal-directed therapy.
- However, this trial has significant limitations and hasn't held up over time, making its findings questionable.
Modern Sepsis Management
- Don't blindly follow outdated practices like excessive fluid administration or PA catheter use.
- Adopt a contemporary, evidence-based approach to sepsis management.
Surviving Sepsis Campaign Origins
- Surviving Sepsis Campaign originated as a marketing effort for specific products related to the Rivers trial.
- The campaign has been slow to adapt to newer evidence, hindering progress in sepsis management.
