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BackTable Vascular & Interventional

Ep. 401 The MOTION Study: Cryoablation for Painful Bone Metastases with Dr. Jack Jennings

Jan 5, 2024
36:36

Episode guests

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Quick takeaways

  • Cryoablation offers effective pain relief for bone metastases near nerves, providing targeted ablation and minimizing nerve damage.
  • Collaboration between interventional radiologists and industry partners drives innovation in interventional oncology, bringing advancements in image guidance and robotics to improve treatment options and expand access to minimally invasive procedures.

Deep dives

Cryo-ablation trial for pain relief in bone metastasis

A prospective international trial was conducted to evaluate the effectiveness of cryo-ablation in treating painful single bone metastasis. The trial enrolled patients with large lesions, with the mean size being 5.7 centimeters. The primary endpoint was a greater than two-point reduction in pain score, and secondary endpoints included opioid use and quality of life. The results showed durable and significant pain relief throughout the six-month follow-up period. The trial also aimed to increase the adoption of cryo-ablation for broader use, emphasizing the importance of expanding treatment options for patients.

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