Becker’s Healthcare Podcast

Dr. Ardeshir Rastinehad, Vice Chair of Urology at Northwell’s Lenox Hill Hospital and System Director for Prostate Cancer at Northwell Health

Dec 7, 2025
Dr. Ardeshir Rastinehad, a dual-trained interventional radiologist and urologic oncologist, dives into the cutting-edge landscape of prostate cancer treatment. He highlights the importance of MRI-based screening and reveals how focal therapy can selectively target cancerous areas, showcasing impressive success rates with cryotherapy. Rastinehad also discusses the burgeoning Focal Therapy Society and the potential for expanding access to minimally invasive procedures, promising a brighter future for patients managing prostate health.
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INSIGHT

Screening Reveals Prostate Cancer Patterns

  • Prostate cancer is common but often low mortality when detected early with imaging-enhanced screening.
  • Gleason/grade group predicts mortality, doubling risk with each higher grade group over time.
ADVICE

Use MRI Before Biopsy

  • Use imaging, ideally MRI, to risk-stratify men with elevated PSA before biopsy.
  • MRI can visualize the entire prostate and guide decisions on whether and where to biopsy.
ANECDOTE

From Bench Work To Patient Questions

  • In 2009 Dr. Rastinehad and colleagues began benchtop and cadaver work on focal therapy using fusion biopsy technology.
  • Northwell validated fusion biopsy in 2012 and patients questioned why whole-gland treatment was needed for localized disease.
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