In this episode we finally conclude our biographical sketch of Isaac Newton by looking at his life in the years following the publication of the Principia.  We look at his political activities following the Glorious Revolution, his friendship with John Locke, the circle of young followers the gathered around him in London, including David Gregory, and his intense and troubled relationship with Nicolas Fatio de Duillier.  We look at the emotional breakdown that took place in 1693 and his work afterwards including his publication of Opticks.  Finally, we consider his legacy though the words of those who followed him.