Global News Podcast The Happy Pod: Hope for people with Huntington's disease
11 snips
Sep 27, 2025 Professor Sarah Tabrizi, a leading Huntington's disease researcher from University College London, discusses groundbreaking gene therapy that shows a 75% reduction in disease progression. This could dramatically improve quality of life for patients. She explains the clinical significance of these results, potential regulatory approval timelines, and how the treatment may change lives. The episode also highlights positive community initiatives, like a Happiness Project in schools and a revitalization effort in Mumbai, showcasing the power of kindness and connection.
AI Snips
Chapters
Transcript
Episode notes
Gene Therapy Dramatically Slows Huntington's
- A new one‑off gene therapy slowed Huntington's clinical progression by about 75% in trial patients.
- That slowdown can keep people functioning and working far longer, dramatically improving quality of life.
Family History Shapes Emotional Response
- Deborah Goodman described multiple relatives who had Huntington's, explaining her emotional reaction to the news.
- She said treatment news made her feel very pleased and grateful to the researchers.
Dose Matters For Clinical And Functional Gain
- The high‑dose group drove the clinical benefit, showing a dose‑dependent effect in the trial.
- High‑dose participants also showed a 60% slowing in functional decline, which is unprecedented.