Stuff You Should Know

How LSD Works

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May 5, 2016
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ANECDOTE

Albert Hofmann's First Acid Trip

  • Albert Hofmann unintentionally absorbed LSD while synthesizing it, leading to the first acid trip.
  • He later intentionally took 250 micrograms, experiencing intense effects on a bike ride home.
ADVICE

LSD Synthesis Is Highly Complex

  • Do not attempt to synthesize LSD; it requires advanced chemistry and dangerous chemicals.
  • The original synthesis uses ergot alkaloids and must be conducted in darkness to avoid decomposition.
ADVICE

Set and Setting Matter Most

  • Always trip in a calm, safe setting with trusted people to ensure a positive experience.
  • Prepare your mindset, as your mental state heavily influences the trip's nature.
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