Q&A with Karen: High Ferritin, Injectable HRT, Breakthrough Bleeding, Optimizing Hormones, Histamine Intolerance and MORE!

Dec 20, 2025

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I'm wrapping up the year by answering your questions in this first of a two-part Q&A, and we cover a lot of ground. From confusing lab results to hormone dosing debates, I dig into the questions so many of you are quietly wondering about. What does high ferritin really mean? Is it iron—or something else entirely?

We'll also take a look at hormone replacement frustrations. Why do some people still bleed months into HRT? Are injections better than patches or creams? And how do you know if your body is actually absorbing what you're taking? I share real-world context, common patterns I see, and why one-size-fits-all advice can be misleading.

This episode also touches on bigger, more nuanced questions. How do genetics like BRCA status factor into hormone decisions? Can stress, immune health, or histamine issues change how hormones affect you? And in perimenopause, is balance even realistic, or are we chasing the wrong goal?

In this episode, we uncover:

How to interpret high ferritin levels and what they may signal beyond iron.
Why hormone absorption issues can cause unexpected symptoms like bleeding.
What typical testosterone and estrogen injection doses actually look like.
How stress, inflammation, and immunity intersect with hormone health.
What to consider when navigating HRT during perimenopause versus menopause.

Tune in now if you've ever felt confused, frustrated, or overwhelmed by hormone advice. Get clarity before we continue the conversation in part two!