The Curbsiders Internal Medicine Podcast #332 Inpatient Covid Management with Dr. Nathan Erdmann
May 2, 2022
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Two Parallel Treatment Arms
- COVID care has two overlapping but distinct arms: antiviral therapy and immune modulation.
- Treating one without considering the other risks mistiming interventions and harming patients.
Use Early Antivirals Or Antibodies
- For patients with risk factors but no oxygen need, consider outpatient monoclonal antibodies or oral antivirals early.
- Use available antibody options and prioritize high-risk or under-boosted patients for these therapies.
Monoclonal Efficacy Is Variant Dependent
- Monoclonal antibody efficacy depends on circulating variants and has changed over time.
- Availability and variant sensitivity must guide which antibody product you choose.