JAMA Medical News Cardiovascular Highlights From AHA Scientific Sessions 2025
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Dec 5, 2025 Join cardiac surgeon Joanna Chikwe, chair of the AHA Scientific Sessions, as she unveils groundbreaking research from the recent meeting. She discusses surprising findings on coffee's relationship with AFib and the promising results of a polypill for heart failure that improves adherence. Joanna also explores a game-changing oral PCSK9 inhibitor and its role in preventing major cardiovascular events. Lastly, she highlights a vitamin D trial post-MI that sparks questions about its long-term benefits. Perfect for anyone interested in cutting-edge cardiovascular advancements!
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Coffee May Not Raise AFib Recurrence
- Longstanding advice to avoid caffeine for atrial fibrillation lacks strong evidence and needed a trial test.
- The trial found continued coffee did not increase AF recurrence and was associated with lower recurrence rates.
Tell Patients Moderate Coffee Is Likely Safe
- Reassure patients who've had cardioversion that moderate natural caffeine (coffee or tea) is probably safe.
- Advise against excessive caffeine and nonnatural caffeinated products in this context.
Polypill Shows Promise For HFrEF
- A polypill combining three proven HFrEF agents modestly improved ejection fraction in a randomized trial.
- The result suggests improved adherence from simplified delivery may drive better outcomes.