DarkHorse Podcast

Hep B or not Hep B: The 303rd Evolutionary Lens with Bret Weinstein and Heather Heying

38 snips
Dec 6, 2025
The discussion kicks off with the CDC's new recommendation to halt Hepatitis B vaccinations for newborns of negative mothers. They delve into the historical reasons behind the initial push for early vaccination and the implications of individual decision-making for parents and doctors. A fascinating study reveals how tattoo ink can affect immune responses to vaccines. Lastly, an homage to the late Tom Stoppard celebrates his genius through reflections on his iconic works, leaving listeners with a profound appreciation of his legacy.
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INSIGHT

ACIP Shifts To Individual Decision-Making

  • ACIP now recommends individual/shared decision-making for Hepatitis B vaccination in infants born to Hep B–negative mothers.
  • Bret Weinstein argues this corrects an earlier unjustified universal birth-dose policy rooted in assumptions of vaccine harmlessness.
INSIGHT

Risk Stratify Hepatitis B Vaccination

  • Hepatitis B rarely infects infants of tested-negative mothers, so population-level birth dosing lacked clear individual benefit.
  • Weinstein and Heying stress risk stratification: vaccinate high-risk infants, not all neonates.
ADVICE

Discuss Hep B With Your Pediatrician

  • Parents should consult clinicians and consider actual household exposure before accepting a neonatal Hep B shot.
  • If no infected household contacts exist, decline the birth dose and reassess later if exposure risk changes.
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