Tryp Rapport Episode 054 - Kratom with Colin
Feb 27, 2024
Dive into the dark side of kratom as Colin shares his harrowing journey with this popular substance. Learn about its pharmacology, the rapid escalation of tolerance, and hidden addiction struggles. Discover why honest conversations about kratom are crucial, especially when marketing often misleads consumers. Colin recounts the mental health crises that led him to seek help and the subsequent cold-turkey recovery that changed his life. Gain insights into the risks, including overdose and contamination, as well as alternatives to help those in need.
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How Kratom Acts On Opioid Receptors
- Kratom contains mitragynine and 7-hydroxymitragynine that partially bind mu-opioid receptors.
- That pharmacology explains both stimulant effects at low doses and opioid-like sedation and pain relief at higher doses.
One-Time Use Led To Immediate Aversion
- Sean tried kratom once for pain and felt like he had consumed alcohol, which he disliked.
- That single intoxicated experience made him stop using kratom entirely.
Rapid Tolerance Causes Physical Strain
- Colin emphasizes kratom produces high tolerance and users start taking massive amounts or extracts.
- That rapid tolerance creates physiological strain and delusional-like symptoms as organs struggle to process the substance.