Global supply chains are cracking up. Even before the pandemic, a confluence of economic and geopolitical factors were accelerating the trend—from rising wages in China to nationalist sentiments sweeping the West, to the beginnings of a U.S.-China decoupling. Rob and Jackie sat down with Chris Caine, president of the Center for Global Enterprise, to break down the reasons for the massive disruption, discuss how different industry sectors are making different strategic calculations, and consider what the future might hold.