ESC TV Today – Your Cardiovascular News Season 3 - Ep.15 : Colchicine for secondary prevention - An algorithmic approach to the workup of syncope
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May 8, 2025 Carlos Aguiar, a cardiologist who presents Cardiology This Week, delves into recent advances in cardiovascular care. He discusses the promising role of colchicine in preventing cardiovascular events, juxtaposed with recent trial findings. The conversation also explores the complexities of diagnosing syncope, especially in older adults, and emphasizes the importance of understanding its mechanisms for better treatment outcomes. Additionally, the Cybis II trial is highlighted for establishing beta blockers as vital therapy in chronic heart failure management.
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Exercise Impact on Heart Health
- Very high exercise volumes lower mortality but don't reduce myocardial infarction risk beyond moderate levels.
- Coronary calcium predicts myocardial infarction risk regardless of exercise volume intensity.
LDL Lowering in Inflammatory Disease
- LDL cholesterol lowering shows greater cardiovascular event reduction in patients with autoimmune or inflammatory diseases.
- Hyperlipidemia and inflammation likely interact synergistically to increase cardiovascular risk.
TAVI and PCI Procedure Safety
- Combined TAVI and complex PCI procedures have more adverse events than staged ones mainly due to bleeding and vascular complications.
- Staged procedures are preferred for patient safety in TAVI and PCI.