What happens when science takes on one of men’s most taboo topics?

In this episode of The Meaning of Men, I speak with John Boghossian, co founder of Kadence Bio, the biotech company developing what could become the first FDA approved treatment for premature ejaculation (PE). John discusses his mission to close what he calls the intimacy gap, the three to one difference in average climax time between men and women, and why solving this issue could positively impact men’s sexual health, confidence, mental wellbeing and relationships.

In this episode you will learn:

What premature ejaculation actually is and why it is far more common than most people realise
How shame, silence and stigma prevent men from seeking support
The science behind Kadence Bio’s on demand treatment and why it represents a breakthrough in sexual health innovation
How improving sexual function can influence mental health, relationship satisfaction and overall quality of life
Why changing cultural narratives around men’s sexual health matters just as much as medical progress

This conversation is about vulnerability, evidence based science and the courage to challenge long standing taboos. It is an essential listen for men and for partners who want a deeper understanding of sexual wellbeing and intimate connection.

Hear more from John:

Website: kadencebio.com LinkedIn linkedin.com/company/kadence-bio X https://x.com/KadenceBio LinkedIn (personal) linkedin.com/in/johnboghossian

Timestamps:

05:22: Understanding Premature Ejaculation 10:16: The Impact of PE on Mental Health and Relationships 12:26: Distinguishing PE from Erectile Dysfunction 15:06: Overcoming Shame and Seeking Help 16:27: Current Treatment Options for PE 19:02: Supporting Partners in Addressing PE 22:51: The Science Behind New Treatments 28:27: Final Thoughts on PE and Seeking Help

#116: “CEOs and organisations are going all-in on Agentic AI.” Dr. Nicola Hodson, Chair, IBM UKI