

37. ARDS: Unpacking Acute Respiratory Distress Syndrome from Pathophysiology to Treatment Approaches
41 snips Nov 18, 2024
Dive deep into Acute Respiratory Distress Syndrome (ARDS), exploring its complex mechanisms and varied treatment strategies. Learn about the essential PaO2 to FiO2 ratio and its role in assessing severity. The hosts discuss innovative ventilation approaches like the '10 Ps' mnemonic and the benefits of prone positioning for better oxygenation. Delve into corticosteroid use, Veno-Venous ECMO, and strategies for fluid management in critical care. The nuances of personalized treatment underscore the importance of tailored patient care in tackling ARDS.
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What is ARDS?
- ARDS (acute respiratory distress syndrome) is an acute, diffuse lung inflammation.
- It's characterized by poor oxygenation and reduced compliance, often leading to respiratory failure.
ARDS Pathophysiology
- ARDS is a final common pathway for various lung injuries.
- It involves inflammation, edema, alveolar collapse, and impaired gas exchange.
Lung Structure and ARDS Impact
- Normal lungs are highly efficient for gas exchange due to a large surface area.
- ARDS disrupts this structure, reducing surface area and increasing the work of breathing.