Nutrition Diva What are senolytics (and should you be taking them)?
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Apr 16, 2025 Dive into the intriguing world of senolytics—compounds aimed at clearing out 'zombie cells' to combat aging. Discover the scientific backing behind these therapies, including promising examples like quercetin. The discussion highlights the significant funding challenges facing anti-aging research and questions the claims surrounding anti-aging supplements. It encourages a critical approach to these products while emphasizing the value of lifestyle changes and nutritious foods in promoting overall health.
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Early Stage of Senolytics Science
- The idea of compounds reversing cellular aging is exciting but currently supported by limited evidence.
- It's too early to say if senolytics are safe, effective, or practical for general human use.
Zombie Cells Drive Aging
- Senescent "zombie" cells are damaged cells that stop dividing but don't die, causing inflammation and tissue damage.
- Removing these cells with senolytics could reduce inflammation and slow aging-related diseases like arthritis and dementia.
Quercetin as a Leading Senolytic
- Quercetin is a natural flavonoid found in many foods that selectively kills senescent cells without harming healthy ones.
- Its established safety profile makes it a leading candidate in senolytic research.