The Biology of Trauma® With Dr. Aimie cover image

The Biology of Trauma® With Dr. Aimie

The Science Behind Why We Can't 'Get Over' Loss And How to Grieve with Dr. Mary-Frances O'Connor

Mar 25, 2025
41:41

“ In order to think about grief, first you have to think about love and bonding, because that is what gets lost. That is what gets broken.”  Dr. Mary-Frances O’Connor

Understanding why grief feels so physical, why someone still reaches for the phone to call someone who's gone, or why certain memories can trigger intense emotions years after a loss can provide valuable insight for those helping others who are experiencing grief or for those who want to know more about grief. And today, we’re diving into the neuroscience behind grief. In this episode, Dr. Mary-Frances O’Connor joins Dr. Aimie to discuss how grief isn't just an emotional response but a complex learning process as our brains adapt to a fundamentally changed reality. She introduces the critical distinction between grief and grieving, highlighting how our attachment patterns influence our grief journey. Her fascinating research on yearning reveals that this powerful sensation activates the same brain regions involved with other basic survival needs, explaining why the feeling can be so intense and overwhelming 

The conversation also goes into how avoidance and rumination can interfere with natural healing, and that the intensity and frequency of grief waves will change over time as part of the grieving process.

 

You’ll learn:

  • The brain regions that activate when you yearn for someone who has died
  • Why yearning is more like hunger or thirst than addiction
  • The difference between grief (response) and grieving (adaptation process)
  • How rumination and avoidance can interfere with natural healing
  • The importance of staying grounded and connected to the present 
  • How to prepare your brain and support systems for future grief experiences
  • The crucial differences between depression and grief, and why they require different approaches

 

Whether you're currently navigating grief, supporting someone who is, or simply preparing for inevitable losses, this episode will help you understand why healing isn’t “getting over” a loss, but an ever evolving process that fundamentally changes our reality.

 

Connect with Dr. O’Connor: Website

Related Podcasts: Episode 42: Unlocking The Role of Disguised Grief in Health  Episode 76: Navigating the Grief Journey: The Polyvagal Way To Become an Active Operator of Your Nervous System  

Guides, Tools & Resources: The Essential Sequence - A free guide that shows you the difference between stress and trauma states of our nervous system. In just 3 steps, it walks you through what your body needs when it has stored trauma or is in a freeze response.  

Foundational Journey - If you want to be safely guided through The Essential Sequence, and lay your foundation of regulation in this online 6 week course, join me and my team of mentors for this journey into your inner world with practical somatic and parts self-practices

Disclaimer: By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others. Consult your own physician for any medical issues that you may be having. This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Trauma Healing Accelerated, any guests or contributors to The Biology of Trauma® podcast, or any employees, associates, or affiliates of Trauma Healing Accelerated be responsible for damages arising from the use of the podcast.

Comment Etiquette: I would love to hear your thoughts on this episode! Please share your constructive feedback by using personal name or initials so that we can keep this space spam-free, and let's keep the discussion positive!

 

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode