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Dust, as defined in the book discussed in this podcast episode, refers to tiny flying particles that are solid and typically about five or ten micrometers in size. Dust plays a significant role in various global processes, including climate regulation, oxygen and nitrogen cycles, and even the ancient climate and deep time. However, it is also a product of economic activities and air pollution, making it the fifth biggest killer on the planet, causing diseases related to particulate air pollution. Dust is intimately linked with water, and human activities such as agriculture and groundwater pumping have led to the creation of dust belts in various regions, resulting in environmental disasters like the Owens Valley in the United States and the Aral Sea in Kazakhstan and Uzbekistan. These dust-producing areas have seen an increase in asthma cases, bronchitis, and other lung diseases, as well as a range of other health issues. Dust is not only a source of concern, but also serves as a valuable tool for researchers, providing insights into ancient climates and offering records of human activity and its impact on the world. Dust and its impact on climate modeling remain areas of unknowns, but efforts are being made to better understand its composition and behavior. Recognizing that dust is a political issue, the book explores the inequalities and power dynamics associated with dust production and its consequences. It also delves into the cultural and historical significance of cleanliness and our pursuit of modernity, where dust is seen as a moral stain. Moreover, the podcast highlights the connection between dust and the making of the modern world, including its role in science, manufacturing, and the creation of technologies. Finally, the podcast discusses the long-lasting legacy of dust-related issues, such as the health consequences of nuclear bomb testing, uranium mining, and the importance of joining the dots to address and mitigate the impact of dust on human health and the environment.