Becker’s Healthcare Podcast Using AI to Power Custom Treatments for Rare Diseases with Steven Ringel
Nov 11, 2025
Join Steven Ringel, CEO of the Kazuna Foundation and Gnome Therapeutics, as he dives into the transformative power of AI in personalized medicine. As an advocate for ultra-rare diseases, he shares his journey from patient to innovator. Discover how AI is revolutionizing custom gene therapies, the latest trends driving personalized treatments, and practical advice for aspiring leaders in healthcare. Ringel emphasizes the importance of passion and self-care in making a meaningful impact—an inspiring listen for those interested in the future of medicine!
AI Snips
Chapters
Transcript
Episode notes
Personal Drive To Build Custom Therapies
- Steven Ringel described becoming an ultra-rare disease patient and sibling after his inherited retinal disease diagnosis at 17.
- That personal experience motivated him to found Kazuna Foundation and later Gnome Therapeutics to build custom gene therapies.
AI Scores Feasibility For Custom Drugs
- Gnome uses AI to aggregate and interpret dozens of databases and produce a 0–100 score indicating feasibility for a custom drug.
- This score helps patients quickly learn whether a personalized therapy is possible and worth pursuing.
Use Gnome's Online Assessment First
- Visit gnome.bio and share limited protected information to get an AI-driven report on whether a custom medicine is feasible for you.
- Use that report to decide next steps and engage Gnome's team if the score indicates high probability.