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PedsCrit

Status Epilepticus with Dr. Manette Ness-Cochinwala and Dr. Anuj Jayakar

Oct 17, 2021
Dr. Manette Ness-Cochinwala and Dr. Anuj Jayakar discuss status epilepticus, its complications, and treatment strategies. Topics include the importance of early recognition, EEG monitoring for high-risk patients, future advancements in treatment options, and the significance of timely diagnosis and treatment.
41:02

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Quick takeaways

  • Early recognition and treatment are crucial for improving outcomes and reducing morbidity in status epilepticus.
  • Continuous EEG monitoring plays a significant role in detecting and managing seizures, optimizing medication dosing, and adjusting treatment plans as needed.

Deep dives

The importance of early recognition and treatment of status epilepticus

Status epilepticus is a common condition that leads to hospitalization, especially in the ICU. Early recognition and treatment are crucial for improving outcomes and reducing morbidity. Seizures lasting longer than 5 minutes are classified as status epilepticus. Treatment usually begins with benzodiazepines, such as lorazepam or diazepam, followed by second-line agents like keppra, fosphenytoin, or valproic acid. If these treatments fail, sedative drips like midazolam may be used. Continuous EEG monitoring is essential for detecting and managing seizures, providing valuable information for adjusting medications. Future developments include the use of new technologies for quicker EEG application and the study of adjunct medications and the ketogenic diet for refractory status epilepticus. Timely intervention is crucial to stop seizures and prevent further brain damage.

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