Sci Guys 134: The Science of Gene Editing & Treating Blindness
Nov 8, 2021
01:01:06
For the first time ever we’ve used CRISPR to edit someone’s genes INSIDE THEIR BODY! So far we’ve been able to reverse some effects of rare genetic eye disease that results in blindness, and this is only the beginning!
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References & Further Reading
- https://medlineplus.gov/genetics/condition/leber-congenital-amaurosis/
- https://rarediseases.info.nih.gov/diseases/634/leber-congenital-amaurosis
- https://luxturna.com
Gene Therapy
- https://www.nature.com/articles/d41586-018-06195-6
- https://www.nature.com/articles/s41587-020-0493-4
- https://www.nature.com/articles/s41573-019-0012-9
The EDIT-101 Trial
- https://clinicaltrials.gov/ct2/show/study/NCT03872479
- https://www.nature.com/articles/s41591-018-0327-9
- https://text.npr.org/2021/09/29/1040879179/vision-loss-crispr-treatment
- https://www.nature.com/articles/d41586-020-00655-8https://www.nature.com/articles/d41586-020-00655-8
- https://jamanetwork.com/journals/jama/fullarticle/2764428https://jamanetwork.com/journals/jama/fullarticle/2764428