
The Jordan Harbinger Show 1272: Left-Handedness | Skeptical Sunday
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Jan 18, 2026 Jessica Wynn, a writer and researcher specializing in science communication, dives into the intriguing world of left-handedness. She reveals that being a lefty isn't just about genetics; it's a mix of prenatal factors and chance. Fascinatingly, ultrasound studies show fetuses exhibit hand preferences early on. Wynn also discusses the brain's wiring in left-handers, leading to enhanced multitasking and creativity. Cultural taboos and historical biases against lefties are explored, shedding light on the unique challenges they face in a right-handed world.
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Handedness Is Multifactorial
- Handedness arises from a mix of genetics, prenatal environment, and random brain development.
- No single gene controls it; small genetic effects plus fetal position and hormones nudge lateralization early on.
TUBB4B Variant Is Correlated, Not Causal
- The rare TUBB4B gene variant appears more often in left-handers but doesn't fully explain left-handedness.
- Identical twins can differ in handedness, showing genes alone aren't determinative.
Womb Behavior Predicts Dominant Hand
- Fetal behavior predicts later handedness: consistent thumb-sucking and head-turn bias show up by ~18 weeks.
- Position and sensory feedback in utero reinforce which side the brain favors long before birth.



