Eye On A.I. #309 Jamie Metzl: Why Gene Editing Needs Governance Or We Lose Control
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Dec 24, 2025 
In this engaging discussion, Jamie Metzl, a futurist and author with expertise in genomics and technology, delves into the critical convergence of artificial intelligence and gene editing. He explores the ethical dilemmas surrounding CRISPR babies and the need for governance to navigate these advancements. Jamie highlights the complexity of genetics, the potential risks of unchecked technological ambition, and the importance of societal values evolving alongside scientific progress. He also discusses the future of healthspan, the implications of AI, and the urgency for equitable governance.
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Prediction That Came True
- Jamie Metzl predicted the first CRISPR babies would be born in China and even listed likely target genes.
- One gene on his list was the one altered by He Jiankui in 2018.
Genome Editing Is Inevitable — Not Yet Responsible
- Humans will eventually edit pre-implanted embryos, but society is not ready now.
- We must build scientific, legal, regulatory, governance and social-norm foundations before large-scale embryo editing.
Build Governance Alongside The Science
- While science advances, invest equal energy in governance, regulation and social norms.
- Avoid letting premature experiments become Nuremberg-style human experimentation driven by wealth or national pride.