Moonshots with Peter Diamandis How I am Reversing My Skins Aging With Peptides w/ Carolina Reis Oliveira | EP #120
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Sep 19, 2024 Carolina Reis Oliveira, co-founder and CEO of OneSkin, dives deep into the science of skin aging. With expertise in stem cell biology and tissue engineering, she explains how senescent cells contribute to aging skin. Carolina shares insights on the revolutionary OS-01 peptide designed to combat these effects and emphasizes the daily importance of sunscreen. The conversation also sheds light on collagen loss and innovative skincare solutions, highlighting the broader implications of maintaining youthful skin for overall well-being.
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Skin Aging Causes
- Skin aging is tissue degeneration caused by internal factors like cell division and mutations.
- External factors include UV exposure, pollution, and smoking, leading to senescent 'zombie' cell buildup and inflammation.
Cellular Senescence
- Human cells have a Hayflick limit of ~50 divisions, after which they should die.
- However, they can become cancerous or senescent, emitting inflammatory molecules, leading to aging.
OneSkin's Origins
- OneSkin started by testing existing anti-aging products on lab-grown human skin.
- They found most were ineffective, leading them to develop their own peptide, OS-01, targeting senescent cells.