Vincent travels to the University of Texas in Austin to speak with speak with Jason McLellan about his career and his research on the SARS-CoV-2 spike protein, including the effect of adding two proline residues, its effect on other viral spike glycoproteins, and general approaches to vaccine design.

Hosts: Vincent Racaniello and Rich Condit

Guest: Jason McLellan

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Links for this episode

MicrobeTV Discord Server
MicrobeTV store at Cafepress
Become a member of ASV (asv.org)
The New City by Dickson Despommier
Prefusion-stabilized SARS-CoV-2 spikes (Science)
Structure-based vaccine design (Curr Opin Immunol)
Prefusion-stabilized SARS-CoV-2 S2-only antigen (Nat Comm)
Stabilized coronavirus spike stem elicits broadly protective antibody (Cell Rep)
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

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TWiV 1103: Jason 'Spike' McLellan