Grant Mitchell, entrepreneur in health and AI, discusses AI in drug repurposing, the Organizational Problem in Pharma, Biomedical Knowledge Graphs, risks in AI-driven drug discovery, neglected knowledge, and the role of translators. He also talks about innovative drug repurposing, the potential of AI in patient relief, constructing biomedical knowledge graphs, and revolutionizing drug repurposing in healthcare.
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Quick takeaways
AI can revolutionize drug repurposing for rare diseases by leveraging biomedical knowledge graphs.
Every Cure focuses on utilizing known drugs for new applications to treat neglected diseases.
The success of repurposing existing drugs like in angiosarcoma reveals untapped potential in innovative treatments.
Deep dives
Mission and Vision of Every Cure
A nonprofit organization focused on repurposing existing drugs to treat diseases that lack effective treatments. The mission is to save lives by leveraging the potential of known drugs for thousands of neglected diseases. The organization aims to address the gaps in the pharmaceutical industry by utilizing AI and collaborative efforts to advance drug discovery.
Utilizing Existing Drugs for Rare Diseases
Every Cure's approach to repurposing existing drugs for rare diseases like Casselman disease highlights the potential to use known drugs for new applications. By leveraging medical knowledge and AI, the organization strives to find treatments for diseases that lack FDA-approved options, offering hope to patients with rare conditions.
Impact of Drug Repurposing on Saving Lives
By focusing on repurposing drugs that are already available and conducting in-depth research on their efficacy for various diseases, Every Cure aims to significantly impact patient outcomes. The success stories of identifying effective treatments using existing drugs, like in angiosarcoma, emphasize the untapped potential for saving lives through innovative approaches.
Building a Global Knowledge Graph for Drug Repurposing
The organization's efforts include constructing a comprehensive biomedical knowledge graph to facilitate drug repurposing initiatives. This platform will provide researchers, physicians, and patients with access to critical data on drug-disease relationships, enabling informed decision-making and accelerating advancements in medical research.
Empowering Individuals to Drive Change
Emphasizing individual responsibility and empowerment, Every Cure encourages people to take the initiative in addressing pressing healthcare challenges. The concept of 'they' highlights the importance of personal agency in driving impactful change and pursuing innovative solutions to complex medical problems. Clarity of vision and proactive communication are key in garnering support and resources for transformative initiatives.
Grant Mitchell is a seasoned entrepreneur, operator, and investor in the areas of health, technology, and machine learning. He is currently the co-founder and CEO of Every Cure, where he uses AI to research rare diseases and conduct drug repurposing.
Grant joins the show to discuss the use of AI in rare drug research, the role of translational scientists, neglected knowledge, and MUCH MORE!