TWiV 222: Jumpin' Jack Flash, it's a GAS GAS GAS

Hosts: Vincent Racaniello, Rich Condit, Dickson Despommier, Alan Dove, and Kathy Spindler

The complete TWiV team discusses the amazing finding that cyclic GMP-AMP synthase is a cytosolic innate immune DNA sensor.

Links for this episode:

• Zhijian J. Chen (Wikipedia)
• Sensing the dark side of DNA (Science)
• cGAMP is an endogenous second messenger (Science)
• cGAMP synthase is a DNA sensor (Science)
• Pore-forming toxin (Wikipedia)
• Letters read on TWiV 222

Weekly Science Picks

Kathy - Graphene batteriesAlan - How do we get cures? (YouTube)Rich - Explosive breach of Condit Dam (Vimeo)Vincent - 10 things you can do to support open access (Tree of Life)

Listener Pick of the Week

Mark - The real story of StuxnetJohn - D-connector virus

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv