Neurosalience

Neurosalience #S1E6 with Michael Fox - Identifying and modulating pathological networks

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Apr 1, 2021
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ANECDOTE

Serendipitous Start in Neuroimaging

  • Michael Fox accidentally started in brain imaging by knocking on the door of Mark Raichle to discuss a poster on the default mode network.
  • This fortuitous encounter sparked his deep interest and career in neuroimaging research.
INSIGHT

Power of Global Signal Regression

  • Global signal regression dramatically enhances anatomical specificity in resting-state fMRI.
  • This step transforms noisy data into clearer functional networks, validating resting-state signals as meaningful.
INSIGHT

Choose Global Signal Regression Wisely

  • Whether or not to apply global signal regression depends on the research question.
  • Removing global signal can eliminate arousal-related signals but enhance underlying anatomical specificity.
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