With fewer children seeking care due to physical distancing, the early detection of pediatric cancers is being impacted. Julie Stern, MD, Director of Outreach Services for the Division of Oncology at Children’s Hospital of Philadelphia, discusses how children with cancer may present differently during the COVID-19 pandemic and how pediatricians can optimize physical exams in telemedicine settings to screen for malignancies, common early presentations of a malignancy to watch for, what to include in initial lab workups, how to reassure parents it’s safe to seek care in this time and more. Published June 2020. This podcast is for general informational and educational purposes only and is not to be considered as medical advice for any particular patient. Clinicians must rely on their own informed clinical judgment in making recommendations to their patients. ©2020 by Children's Hospital of Philadelphia, all rights reserved.