More than half of infants experience gastroesophageal reflux (GER) and 10-20% have gastroesophageal reflux disease (GERD), and guidelines for this issue often change. Here to help clear up confusion is Jefferson Brownell, MD, pediatric gastroenterologist, Children’s Hospital of Philadelphia. He first provides a review of red flags for referral to GI or the emergency room, and then an overview of GERD in otherwise healthy babies, including: scheduled small-volume feedings; thickening options; amino acid formulas and other formula options; positioning during sleep; medication options; duration of meds and how to wean; counseling families hesitant to start meds; and more. This podcast is for general informational and educational purposes only and is not to be considered as medical advice for any particular patient. Clinicians must rely on their own informed clinical judgment in making recommendations to their patients. ©2022 by Children's Hospital of Philadelphia, all rights reserved.