The Radiopaedia Reading Room Podcast 59. Neuroradiology: Inflammatory brain diseases & IIH
Feb 3, 2025
Francis Deng is joined by Tabby Kennedy, an associate professor specializing in neuroinflammatory diseases, and Tom Campion from Barts Health NHS Trust. They dive deep into the complexities of diagnosing non-MS inflammatory brain diseases and idiopathic intracranial hypertension (IIH). The trio discusses advanced imaging techniques, the significance of antibody testing, and the challenges in differentiating conditions like lymphoma from inflammatory disorders. They also explore the role of AI in radiology and the diagnostic nuances of IIH, emphasizing imaging correlations with clinical symptoms.
AI Snips
Chapters
Transcript
Episode notes
Master MS Imaging First
- Get very good at MS imaging first to recognise typical presentations and variations.
- Use neuroinflammatory MDTs and many MS cases to spot red flags that suggest other diagnoses.
Test Early For Autoantibodies
- Send antibody tests (MOG, AQP4/NMO) early when features are atypical or optic neuritis is unusual.
- Order antibodies quickly if bilateral, chiasmal, posterior or long-segment optic nerve involvement appears.
Imaging Shapes New Disease Recognition
- Neuroradiologists can shape recognition of new antibody-defined diseases by curating imaging phenotypes.
- Building case libraries and sharing patterns at conferences helps those diseases emerge diagnostically.