Eagle's Eye View: Your Weekly CV Update From ACC.org Weight Management in Pregnancy and CVD Risk; Impact of Statins Plus Ezetimibe Post-MI; PARTNER-3 Study 5-year Results
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Apr 23, 2025 Discover how weight management during pregnancy can impact cardiovascular disease risk. Learn about the promising effects of adding ezetimibe to statin therapy post-myocardial infarction. Explore the five-year results of the pivotal PARTNER-3 study, comparing outcomes between transcatheter and surgical aortic valve replacements. These insights reveal crucial connections between pregnancy, heart health, and innovative treatment strategies.
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Pregnancy Weight and Cardiovascular Risk
- Weight management before pregnancy influences future cardiovascular risk.
- Pregnancy complications mediate this risk through effects on blood pressure and glucose control.
Early Ezetimibe Plus Statin Post-MI
- Early combination of ezetimibe and statin post-MI reduces major cardiovascular events.
- Achieving LDL below 55 mg/dL is key to improved outcomes in this setting.
Five-Year PARTNER-3 TAVR Insights
- TAVR shows good five-year echocardiographic and clinical outcomes vs SAVR in low-risk aortic stenosis.
- Differences include more aortic regurgitation and higher valve gradients but larger valve area in TAVR patients.