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In this episode of the Psychedelic Therapy Frontiers podcast Dr. Steve Thayer and Dr. Reid Robison discuss the question, “Can psychedelics make you feel worse?” They define what is meant by “worse”; discuss preparation, navigation, and integration factors that effect the outcome of a psychedelic experience; list some contraindications for psychedelic use; explore the relationship between suffering and meaning; talk about neurophysiological reasons people sometimes feel worse after psychedelics, and much more.

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