136: The Autonomic Deregulation Theory of Aging

In this episode, we share highlights from a recent Biohacker Expo talk, exploring why we age and how the autonomic nervous system, especially the vagus nerve, plays a central role in the process. We break down compelling research, like Nobel Prize-winning discoveries by Shinya Yamanaka and the promising work of experts in reversing aging. Together, we sort aging’s hallmarks into categories including energy, information, and homeostasis, showing how autonomic balance influences everything from mitochondria and epigenetics to immune function and cellular renewal.

Throughout the conversation, we discuss the impact of chronic stress and why supporting parasympathetic activity can decelerate aging. We explain how everyday habits (diet, brain and body exercise, sleep, fasting, and even neurostimulation) can help maintain cellular health and slow the aging clock. Practical recommendations are given, including the latest vagus nerve technology and classic mindfulness approaches, making the science accessible and actionable.

Share this episode with someone curious about longevity or improving their vitality. If you’re a clinician or biohacker, use these insights to inspire new approaches and upgrade your health journey. We’d love to see you embrace these tools and help others benefit too.

Dr. Navaz Habib

Email: podcast@healthupgraded.com
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JP Errico
Instagram: https://www.instagram.com/thevnsguy/
LinkedIn: https://www.linkedin.com/in/jp-errico-097629aa