This episode is brought to you by LMNT and Fatty15.

By conservative estimates, over half of Americans suffer from insulin resistance—a pathway that can lead to numerous chronic diseases. Fortunately, this is not a one-way street; we have the power to change course and protect our long-term health.

Today on The Dhru Purohit Show, we bring you a special compilation episode featuring Dhru's conversations with leading experts on the dangers of insulin resistance.

Dhru sits down with Kristin Kirkpatrick and Dr. Ibrahim Hanouneh to discuss an epidemic affecting one in four people: non-alcoholic fatty liver disease (NAFLD) and its connection to insulin resistance. Kristin and Dr. Hanouneh highlight the most significant risk factors for fatty liver disease, including metabolic dysfunction and diabetes. They also delve into how ultra-processed foods, excessive sugar consumption, and sedentary lifestyles contribute to the rise in NAFLD cases.

Additionally, Dr. Morgan Nolte explains why weight gain and insulin resistance are becoming more prevalent and shares actionable strategies to improve our relationship with insulin. She breaks down how insulin resistance changes as we age and emphasizes the transformative power of optimal fiber intake, quality sleep, stress reduction, and strength training in maintaining metabolic health and achieving an ideal weight.

Kristin Kirkpatrick, MS, RDN, is a celebrated author, speaker, and accomplished dietitian with over 25 years of experience. She is a dietitian at the Cleveland Clinic Department of Wellness & Preventive Medicine.

Dr. Ibrahim Hanouneh, MD, is a gastroenterologist and hepatologist specializing in liver disease. He served as Chief Gastroenterology Fellow and associate staff at the Cleveland Clinic and later contributed his expertise to Minnesota Gastroenterology and Mayo Clinic in Minnesota.

Dr. Morgan Nolte is a board-certified clinical specialist in geriatric physical therapy. She recognized a need for preventative education and care that focuses on reversing risk factors instead of just treating symptoms. That led her to focus on developing online courses and coaching programs that help adults reverse insulin resistance for long-term weight loss and disease prevention.

In this episode, Dhru and his guests dive into:

Why we need to focus on insulin resistance (00:00:05)
Biggest warning signs of fatty liver disease (2:04)
Role of the liver (6:48)
The pathway that leads to fatty liver (9:53)
Myths about fatty liver and the major culprit of fatty liver disease (13:12)
How non-alcoholic fatty liver gets in the way of our long-term health and chronic inflammation (18:32)
Why insulin is crucial (25:06)
Why insulin resistance changes as we age (31:27)
Toxic traits that damage mindset (39:31)
Pillars of nutrition (46:00)
Optimizing muscle mass for those in the healthy baseline (51:51)
Importance of sleep on your appetite (55:46)
Strength training and stress management for optimal insulin levels (1:02:51)

Also mentioned:

Regenerative Health Book

This episode is brought to you by LMNT and Fatty15.

Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today.

Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health.

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03/19/2025 | World News Roundup Late Edition