Heart Podcast Cardiovascular risk in patients with chronic kidney disease
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Dec 3, 2024 Mark Sarnak, an expert from Tufts University, discusses the intricate relationship between chronic kidney disease (CKD) and cardiovascular risks. He highlights the rising incidence of CKD driven by obesity and diabetes, and the significance of efficient screening. Sarnak delves into the latest guidelines for managing cardiovascular risk in CKD patients, including the use of innovative treatments like SGLT2 inhibitors. He also touches on the complexities of prescribing antiplatelet medications and the future of personalized medicine in cardiovascular care.
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CKD Prevalence
- Chronic kidney disease (CKD) affects 10-15% of the population, possibly even more due to its silent nature.
- The prevalence is increasing due to obesity, diabetes, and aging.
CKD and Cardiovascular Risk
- CKD significantly increases cardiovascular disease risk, independent of other risk factors.
- The risk increases with higher albuminuria and lower GFR, affecting all types of cardiovascular disease.
Mechanisms of Increased Risk
- CKD reflects the severity of traditional risk factors like hypertension and diabetes.
- It also involves non-traditional factors like mineral metabolism abnormalities and inflammation.