The Intern At Work: Internal Medicine cover image

The Intern At Work: Internal Medicine

102. An Emphasis on Bronchiectasis

Aug 15, 2021
Drs. Aram Karkar and Yassmin Behzadian, along with other medical professionals, discuss bronchiectasis, including its causes, diagnostic work-up, treatment options, and the impact of the EMBRACE trial on treatment guidelines. They also highlight the effectiveness of azithromycin in managing bronchiectasis.
17:44

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Quick takeaways

  • The Lady Windermere Syndrome can lead to mycobacterium infections in older women by suppressing the cough reflex.
  • Chronic inflammation affects mucus clearance and leads to structural airway changes in bronchiectasis pathogenesis.

Deep dives

Understanding Bronchiectasis and Lady Windermere Syndrome

Bronchiectasis is a chronic lung disease characterized by the abnormal dilation of airways. The Lady Windermere Syndrome refers to a presentation seen particularly in older women without underlying lung disease who suppress their cough reflex, making them susceptible to mycobacterium infections. This syndrome, although debated in terms of mechanism, is part of the bronchiectasis spectrum.

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