Radically Genuine Podcast with Dr. Roger McFillin 196. Can Microdosing Psilocybin Revolutionize Mental Health?
Aug 14, 2025
Charity Mills, CEO of Colorado Teletherapy Services and a leading voice in psilocybin microdosing, dives into the promising therapeutic potential of mushrooms. She shares her insights on how microdosing can be a game-changer for mental health, especially for those who feel let down by traditional treatments. The conversation shines a light on navigating psilocybin's legality, the importance of dosage, and its ability to foster creativity and mindfulness. Charity's personal journey and clinical experiences offer a powerful perspective on this evolving frontier.
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Psilocybin Rewires Brain Connectivity
- Psilocybin binds the 5-HT2A serotonin receptor and makes brain regions communicate differently.
- That cross-talk can reveal hidden perspectives and enable therapeutic shifts.
Teletubbies Trip Taught Importance Of Set
- Charity described a bad early mushroom trip born from lack of preparation and no purpose.
- She learned that intention, set and setting matter for any psychedelic work.
Start With Small, Daily Doses
- Microdosing uses about one-tenth of a macrodose and lets you carry on daily life.
- Expect 0.1–0.5 grams (100–500 mg) and tailor the amount to your experience.