

July 2024: Obstetrics
Jun 24, 2024
Dr. Holly B. Ende, an expert in obstetric anesthesiology at Vanderbilt University Medical Center, dives into groundbreaking advancements in postpartum hemorrhage risk prediction. She discusses the development of a real-time predictive model, emphasizing its integration into clinical settings for better patient outcomes. The podcast also highlights the importance of validating these models within electronic health records to enhance healthcare provider efficiency and improve maternal care. Listeners will gain insights into the urgency of timely interventions and the collaborative efforts to refine clinical prediction tools.
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MAP Links To Neonatal Harm
- Increasing mean arterial pressure during pregnancy was associated with worse neonatal outcomes in the CHAP trial cohort.
- Optimal MAP thresholds for balancing fetal and maternal benefits remain uncertain and need further study.
Monitor PTT With Gestational Heparin Dosing
- Gestational age–based heparin dosing increased abnormal elevated PTTs compared with fixed dosing in antepartum patients.
- If you use gestational age–based dosing, monitor PTT closely to detect coagulation changes.
PPH Is Preventable With Faster Recognition
- Postpartum hemorrhage is a leading cause of maternal morbidity and most hemorrhage deaths are preventable.
- Predictive models could reduce delays in recognition and treatment that lead to preventable deaths.