Short Wave

'Zombie' Cells Could Explain Aging — And Help Scientists Slow It

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Aug 5, 2025
Freelance science journalist Diana Kwon explores the intriguing link between stress and aging. She discusses groundbreaking research showing how stress alters our DNA, mimicking aging effects. The conversation uncovers 'zombie cells'—aging cells that sap resources from healthier ones—and their role in cognitive decline. Kwon highlights GDF-15, a key molecule involved in cellular stress signaling, and hints at potential lifestyle changes and treatments that could reverse stress-related aging. It’s a captivating look at how science may unlock healthier aging!
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ANECDOTE

Stress Speeds Biological Aging

  • Researchers studied stress in mothers of chronically ill children, finding higher stress levels.
  • They discovered these stressed parents had shorter telomeres, indicating biological aging.
INSIGHT

Zombie Cells Accelerate Aging

  • Chronic stress increases senescent or zombie cells that stop dividing and drain resources.
  • These cells contribute to aging by impairing overall cellular function and health.
INSIGHT

Brain Energy Reallocation Causes Aging

  • The brain-body energy conservation model posits the brain reallocates energy to repair old, damaged cells.
  • This energy diversion causes aging signs like graying hair and muscle loss by sacrificing less vital functions.
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