Progress, Potential, and Possibilities Podcast / Show Dr. Jacob Hanna, MD, PhD - Synthetic Embryo R&D In Regenerative Medicine And Developmental Biology
Dr. Jacob Hanna, MD, Ph.D. ( https://hannalabweb.weizmann.ac.il/ ) is a Senior Scientist and Professor in the Department of Molecular Genetics at the Weizmann Institute of Science in Israel, where his lab, and the interdisciplinary group of scientists within it, are focused on understanding the complexity of early embryonic stem cell biology and early developmental dynamics, as well as advancing human disease modeling. More specifically, Dr. Hanna's lab investigates the detailed process of cellular reprogramming, in which induced pluripotent stem cells are generated from somatic cells, and they investigate how pluripotency is maintained throughout development in mouse and human. In their studies they employ a diverse arsenal of biological experimentation methods, high throughput screening, advanced microscopy and genomic analyses seeking to combine biological experimentation with computational biology, theory and modeling, to elucidate various biological questions. Dr. Hanna completed both his MD and PhD at The Hebrew University of Jerusalem, where his work was focused in the domain of immunology with his thesis focus on novel molecular and functional properties of human NK Subsets. He then went on to do postdoctoral studies at the Whitehead Institute for Biomedical Research at MIT under the tutelage of Prof. Dr. Rudolf Jaenisch with a field of study of pluripotency and epigenetic reprogramming. Dr. Hanna is also Founder and Chief Scientific Advisor, of Renewal Bio ( https://www.renewal.bio/ ), a biotech company looking to leverage the power of these new stem cell technologies, potentially applying them to a wide variety of human ailments including infertility, genetic diseases, and longevity.