Isoniazid (Niazid)

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Generic Name

isoniazide

Trade Name

INH

Indication

tuberculosis

Action

Inhibits synthesis of mycobacterial cell wall

Therapeutic Class

Antitubercular

Pharmacologic Class

none

Nursing Considerations

• can cause jaundice • may cause peripheral neuropathy, seizures, hepatitis • patient should avoid high amounts of tyramine (pickled meats, aged/smoked meats, alcohol, exotic/aged cheese) • monitor liver function tests • complete full course of therapy (6-12 months) • often used in combination with Rifampin