1053-Revolutionizing Opioid and Trauma Treatment with Neurostimulation

Introduction to Neurostimulation in Recovery

• Neurostimulation techniques, like vagus nerve stimulation (VNS), have been researched for their role in treating neurological diseases, including addiction and trauma-related disorders.
• Dr. Navid Kodaparash shares his insights into how neuroplasticity, triggered through VNS, helps the brain recover and adapt.

Autonomic Nervous System and Its Role

• The autonomic nervous system consists of the sympathetic (fight-or-flight) and parasympathetic (rest-and-digest) systems, which work in tandem to regulate stress responses.
• Dysregulation of this system, especially in chronic stress or trauma, can lead to conditions like PTSD, anxiety, and addiction.

Vagus Nerve: The Wandering Nerve

• The vagus nerve is crucial for regulating the parasympathetic nervous system. It's known as the "wandering nerve" because it connects multiple organs in the body.
• Stimulating the vagus nerve can promote a calming effect, reducing heart rate and helping the body relax.

Vagal Tone and Stress Regulation

• Poor vagal tone refers to reduced parasympathetic activity, leading to higher stress and anxiety levels. Improving vagal tone can enhance overall emotional regulation.
• Techniques like breathing exercises and auricular vagus nerve stimulation can help improve vagal tone over time.

Neurostimulation for Addiction and Trauma

• Chronic stress and trauma predispose individuals to self-medicate with substances like opioids, leading to addiction.
• Neurostimulation techniques, including auricular vagus nerve stimulation (aVNS), show promise in reducing symptoms of post-acute withdrawal syndrome (PAWS) and anxiety during recovery from opioid use disorder.

Non-Invasive VNS

• Non-invasive VNS techniques, like ear stimulation, can offer similar benefits to implanted devices without requiring surgery. These methods have shown success in managing stress, trauma, and addiction recovery.

Clinical Trials and Treatment

• Sparrow biomedical devices are currently being researched for their effectiveness in treating opioid withdrawal and chronic pain management.
• Trials have demonstrated the efficacy of VNS in reducing withdrawal symptoms and shortening recovery times for patients suffering from opioid dependency.

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