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Mendelspod Podcast

Big RNA with Brendan Frey of Deep Genomics

Jan 30, 2025
06:13
This is a free preview of a paid episode. To hear more, visit www.mendelspod.com

In our first conversation with Deep Genomics, Theral sits down with Brendan Frey, the company's founder and Chief Innovation Officer, to explore the power of AI in RNA biology and drug discovery. Frey, a pioneer in deep learning who trained in the lab of AI luminary Geoffrey Hinton, shares how his personal experience in genetics back in 2002 led him to merge machine learning with genomic medicine. The company has a head start.

In the past year, Deep Genomics has built Big RNA, the first foundational model for RNA biology, trained on over a trillion genomic signals.

"RNA is the ideal point of intervention," says Frey. "It’s the software of biology—it takes context into account, shaping how DNA functions across different cells and conditions."

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