Core IM | Internal Medicine Podcast
#139 CKD Staging (Cr vs. Cystatin C, Albuminuria & more): Mind The Gap Segment
Nov 8, 2023
Explore the pros and cons of using Cr or Cystatin C to assess eGFR in CKD staging. Learn about the limitations of creatinine as a biomarker for kidney function and the importance of considering glomerular filtration rate and albuminuria. Discover the implications of low GFR in patient care, the advantages of using cystatin C and measuring albuminuria, and the flaws of using creatinine in evaluating renal function.
26:27
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Quick takeaways
- CKD staging is important for identifying patients at different stages of the disease and implementing appropriate interventions.
- Cystatin C is a superior biomarker for estimating GFR as it is not influenced by skeletal muscle mass and tubular secretion, unlike creatinine.
Deep dives
The Importance of CKD Staging
One of the main topics discussed in this podcast is the importance of staging chronic kidney disease (CKD). The hosts emphasize that although CKD staging can seem boring and full of technical terms, it is crucial for identifying patients at different stages of the disease and implementing appropriate interventions. CKD staging includes both the G-stage, which measures the glomerular filtration rate (GFR), and the A-stage, which measures albuminuria. The hosts explain the different stages of GFR and albuminuria and stress the significance of identifying patients with proteinuria for targeted renal therapies and risk factor modification.
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