Olanzapine (Zyprexa) Nursing Considerations

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olanzapine

Trade Name

Zyprexa

Indication

schizophrenia, mania, depression, anorexia nervosa, nausea/vomiting related to chemotherapy

Action

antagonizes dopamine and serotonin

Therapeutic Class

antipsychotic, mood stabilizers

Pharmacologic Class

thienobenzodiazepines

Nursing Considerations

• do not use while breastfeeding • can cause neurolyptic malignant syndrome, seizures, suicidal thoughts, insomnia, tardive dyskinesia, agranulocytosis, constipation, tremors • assess mental status • monitor hemodynamics • assess blood sugars • assess intake and output • monitor liver function tests