CortexCast - A Neuroscience Podcast cover image

CortexCast - A Neuroscience Podcast

Facing Depression - Catherine Harmer

May 28, 2020
Professor Catherine Harmer, an expert in emotional processing and depression, shares insights into the brain mechanisms behind depression. She delves into the effects of antidepressant medications on emotional responses, revealing how cognitive biases shape perceptions in those affected. Catherine also discusses innovative treatments, including rapid-acting antidepressants and brain stimulation. Additionally, she offers advice for graduate students on navigating research challenges and emphasizes the importance of balancing academic pursuits with personal passions.
48:49

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Quick takeaways

  • Depressed individuals often exhibit a negative bias in emotional processing, misinterpreting social cues and worsening their condition.
  • Advancements in personalized treatment approaches and fast-acting antidepressants hold promise for revolutionizing depression therapies.

Deep dives

The Emotional Processing Bias in Depression

Individuals prone to depression tend to focus on negative information, which significantly impacts their emotional processing. This negative bias can lead them to misinterpret social interactions, perceiving neutral or even positive facial expressions as negative, such as disgust or anger. These misinterpretations can affect their behavior, causing them to withdraw from social situations, which can further exacerbate feelings of depression. Understanding this emotional processing bias is crucial for developing effective interventions and treatments for depression.

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