This week on The Genetics Podcast, Patrick is joined by Kent Rogers, Chief Executive Officer at EveryONE Medicines. They discuss Kent’s journey across every side of the desk in the drug discovery space, EveryONE Medicines’ efforts to develop antisense oligonucleotides for ultra-rare diseases, and the need to adapt regulatory models for n-of-1 therapies.

Show Notes:

00:00 Intro to The Genetics Podcast

00:59 Welcome to Kent and his experiences across every side of the pharma ‘desk’

06:00 Challenges of commercialization for ultra-rare disease therapies and the advantage of antisense oligonucleotides (ASOs)

10:28 EveryONE Medicines’ approach to regulatory bodies

12:30 Regulatory feedback and expectations from EveryONE Medicines’ platform-based approach to n-of-1 therapies

15:47 Differences in regulatory requirements for rare disease across countries

19:53 Insights from being on different sides of the drug development industry

22:40 Differences in healthcare systems across countries that can facilitate or impede drug development

26:57 Rationale behind focusing on ASOs for treating rare diseases

28:03 Building EveryONE Medicines and Kent’s approach to leadership

33:20 Lessons from Kent’s career

37:17 Closing remarks

Find out more

EveryONE Medicines (https://www.eomeds.com/)

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