Show notes⁠ / Don't Die is more than just another health book. It mixes philosophy with science. Johnson sees aging as a disease we can beat.

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IN THIS EPISODE: Tech entrepreneur Brian Johnson proposes a radical, scientifically-backed approach to defeating aging through comprehensive health monitoring, strict lifestyle protocols, and cutting-edge experimental interventions.

TOPICS: Longevity, nutrition, health, technology, biology

KEY FIGURES: PayPal, Brian Johnson, CRISPR, Braintree, National Institute on Aging, don't die, StoryShots, Dr. Oliver Zollman, Blueprint Protocol

SUMMARY:

Brian Johnson, a tech entrepreneur and author of 'Don't Die', has developed an extreme approach to longevity that involves meticulously tracking and optimizing his health. At 47, he claims to have the body of an 18-year-old through a rigorous regimen that includes a strict 1,977-calorie vegan diet consumed within a five-hour window, taking over 100 pills daily, and following a comprehensive health protocol called Blueprint that monitors 81 different body systems.

Johnson's methodology goes beyond traditional health practices, treating aging as a disease that can be conquered through systematic interventions. He uses advanced health tracking, including DNA methylation testing and inflammation markers, to guide his daily routines. His approach involves experimental therapies like blood exchange with his son and father, gene therapy interventions, and a unique sleep optimization strategy that creates an ideal rest environment.

While Johnson's methods are controversial and expensive, costing over $2 million annually, he believes his work will eventually benefit everyone by pushing the boundaries of longevity research. His book 'Don't Die' presents a philosophical framework for understanding aging, emphasizing that most people live in 'slow suicide' by making short-term choices that harm long-term health. Johnson envisions a future where technology like gene editing, AI, and advanced biotechnology will make radical life extension possible and accessible.

KEY QUOTES:

• "As a species, we accept our decay, decline and death. I want to argue that the opposite should be true." - Brian Johnson

• "Johnson says most people live in slow suicide. They make choices that feel good now but hurt their future selves." - Brian Johnson

• "Johnson compares our body to computer software. We can update the code." - Brian Johnson

• "Change is hard. Being miserable is harder." - Brian Johnson

• "Before any decision, ask does this help me not die?" - Brian Johnson

KEY TAKEAWAYS:

• Brian Johnson views aging as a disease that can be 'solved' through systematic, data-driven interventions, spending over $2 million annually to track and potentially reverse his biological aging

• Johnson's 'Don't Die' philosophy involves making every lifestyle choice through the lens of whether it helps or hurts long-term survival, including a strict 1,977-calorie vegan diet consumed within a 5-hour window and taking over 100 supplements daily

• Johnson tracks 81 different body systems using advanced biomarkers like DNA methylation and inflammation markers, allowing him to make real-time adjustments to his health protocols

• His approach combines cutting-edge experimental treatments like blood exchange with his son and gene therapy interventions, while acknowledging the current scientific uncertainty of these methods...

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Episode #26: 2023 Year in Review