Surprise Visit From Martin Shkreli, Range Rover Launches New Logo, Timeline Reactions | Martin Shkreli, Joe Weisenthal, Joseph Krause, Nirav Tolia, Mike Knoop, Kyle Samani

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Jul 18, 2025

Guest

Nirav Tolia

Martin Shkreli, a controversial entrepreneur and former pharma exec, makes a surprising appearance. He dives into his current project aimed at competing with Bloomberg. Joe Weisenthal shares insights on the shifting dynamics in finance and the need for innovation. Meanwhile, Mike Knoop highlights the role of AI in generalization tasks. Joseph Krause discusses Radical AI's impressive funding and future plans, while Kyle Samani explores stablecoins' transformative potential. Nirav Tolia elaborates on Nextdoor's redesign to boost community engagement.

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ANECDOTE

Martin Shkreli's Early Trading Anecdote

Martin Shkreli shared his experience working at Jim Cramer's hedge fund and Tiger Cub firms as a young analyst.
He described the intense trading environment, including being nearly hit by a thrown computer monitor.

INSIGHT

Financial Firms' Hidden Value

Martin Shkreli argued a financial information company could be worth a trillion dollars if well run.
He estimated Michael Bloomberg's true wealth could be hundreds of billions due to his family office investments.

INSIGHT

Bloomberg's Social Network Value

The value of the Bloomberg terminal lies largely in its social network component.
Wall Street traders use it as an exclusive communication platform beyond just data.

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(01:19) - Timeline
(20:53) - Range Rover Launches New Logo
(29:07) - Martin Shkreli. Martin is an American entrepreneur and former pharmaceutical executive known for his work in biotechnology and hedge fund management. He co-founded the hedge funds Elea Capital, MSMB Capital Management, and the biopharmaceutical companies Retrophin and Turing Pharmaceuticals. Shkreli gained national attention during his tenure at Turing, and later faced legal issues related to securities fraud, for which he was convicted in 2017. Despite his controversial public image, he remains a notable figure in the biotech and finance communities.
(01:21:40) - Timeline
(01:36:11) - Joseph Krause, co-founder and CEO of Radical AI, announced the company's $55 million seed funding round, led by RTX Ventures, marking one of the largest in New York's history. He discussed plans to build an advanced materials R&D facility integrating AI and robotics to accelerate materials science innovation. Krause also shared his background in nanoscience and the journey from academic research to entrepreneurship, emphasizing the importance of culture and lean operations in their growth strategy.
(01:45:29) - Timeline
(01:53:20) - Joe Weisenthal is an American journalist and financial expert. He serves as the executive editor of news for Bloomberg Digital, co-anchors Bloomberg Television's "What’d You Miss?", and co-hosts the "Odd Lots" podcast. In the conversation, Weisenthal discusses recent positive economic data, including better-than-expected retail sales and jobless claims, and explores the implications of potential Federal Reserve rate cuts on long-term interest rates and mortgage rates.
(02:23:53) - Nirav Tolia, co-founder and CEO of Nextdoor, recently discussed the platform's comprehensive redesign aimed at enhancing user engagement and utility. The new Nextdoor introduces three core features: 'News,' integrating content from over 3,500 local publications; 'Alerts,' providing real-time updates on local emergencies; and 'Faves,' an AI-powered tool offering personalized recommendations based on neighborhood conversations. Tolia emphasized that these enhancements are designed to make Nextdoor an indispensable daily resource for neighbors, fostering stronger, safer, and more connected communities.
(02:40:13) - Mike Knoop, co-founder of Zapier and host of the ARC Prize, discusses the ARC-AGI benchmark's role in measuring AI's ability to generalize on novel tasks, emphasizing that while AI systems have made progress, they still lag behind human efficiency levels. He highlights the ARC Prize's aim to accelerate AGI development by encouraging open sharing of new ideas and fostering a diverse AI research community. Knoop also introduces ARC V3, an interactive reasoning benchmark designed to challenge emerging AI agent systems, noting its increased complexity and the importance of efficiency constraints to prevent agents from relying on brute-force methods.
(03:00:58) - Kyle Samani, co-founder and managing partner at Multicoin Capital, discusses the transformative potential of stablecoins in enabling global access to U.S. dollars, emphasizing that this unprecedented shift is not yet fully appreciated. He highlights the profound implications for global commerce and payments, noting that major consumer software platforms can now legally integrate stablecoins, potentially onboarding billions of users into the crypto ecosystem. Samani also touches on the evolving regulatory landscape, mentioning the passage of the Genius Act and the anticipated Clarity Act, which aim to define regulatory responsibilities and provide clarity for the industry.

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